Table 6.
Results of Multivariable Analysis.
| A—Multivariable analysis for in-hospital mortality | |||||
|---|---|---|---|---|---|
| Coefficient (B) | Standard Error of B | Odds Ratio | 95% Confidence Interval | P-Value | |
| Albumin | −0.925 | 0.282 | 0.40 | 0.23-0.69 | < .001 |
| SaO2 (%) | −0.051 | 0.023 | 0.95 | 0.90-0.99 | .02 |
| BNP | 0.0002 | 0.00006 | 1.0002 | 1.0001-1.0003 | < .001 |
| Hypercoagulable state | 1.120 | 0.383 | 3.07 | 1.45-6.49 | < .01 |
| PESI score ≥ 104.5 | 1.380 | 0.632 | 3.98 | 1.15-13.73 | .03 |
| Variables included in the model: Sex, weight, ACC/AHA low risk, ACC/AHA massive, hypercoagulable state, provoked VTE, HR, SBP, RR, SaO2, Temperature, AMS, BUN, troponin I, BNP, lactate, albumin. Fluid electrolyte disorder, cancer diagnosis, obesity, recent weight loss, history of anemia, PESI ≥ 104.5, sPESI ≥ 2, CCI ≥ 6, ECI ≥15.5. | |||||
| B—Multivariable analysis for 90-day mortality | |||||
| Albumin | −0.800 | 0.230 | 0.450 | 0.29-0.71 | < .001 |
| History of anemia/Sickle | 0.641 | 0.317 | 1.90 | 1.02-3.53 | .04 |
| BNP | 0.00015 | 0.00005 | 1.0002 | 1.000041-1.00026 | < .001 |
| Hypercoagulable state | 0.901 | 0.302 | 2.46 | 1.36-4.44 | < .01 |
| PESI Score ≥ 121.5 | 0.752 | 0.328 | 2.12 | 1.12-4.03 | .02 |
| Variables included in the model: Sex, weight, ACC/AHA low risk, hypercoagulable state, provoked VTE, SBP, RR, chest pain, AMS, BUN, troponin I, BNP, lactate, albumin. Fluid electrolyte disorder, cancer diagnosis, obesity, recent weight loss, history of anemia, PESI ≥121.5, sPESI ≥ 2, CCI ≥6, ECI ≥15.5. | |||||
| C—Multivariable analysis for overall mortality | |||||
| Albumin | −0.564 | 0.177 | 0.57 | 0.40-0.80 | < .01 |
| Weight | −0.021 | 0.006 | 0.98 | 0.97-0.99 | < .01 |
| BUN | 0.014 | 0.006 | 1.014 | 1.003-1.03 | .01 |
| BNP | 0.00011 | 0.00006 | 1.0001 | 1.000005-1.00022 | .02 |
| History of anemia/Sickle | 0.536 | 0.250 | 1.71 | 1.05-2.79 | .03 |
| Cardiac arrhythmia | 0.604 | 0.272 | 1.83 | 1.07-3.11 | .03 |
| PESI Score ≥ 121.5 | 0.865 | 0.243 | 2.37 | 1.47-3.82 | < .001 |
| Charlson Score ≥ 5 | 1.142 | 0.230 | 3.13 | 1.99-4.91 | < .001 |
| Variables included in the model: Age, weight, ACC/AHA low risk, hypercoagulable state, provoked VTE, SBP, temperature, chest pain, AMS, BUN, troponin I, BNP, lactate, albumin, CHF, Cardiac arrythmia, CKD, cancer diagnosis, obesity, recent weight loss, history of anemia, history of major bleeding, organ transplantation, PESI ≥ 121.5, sPESI ≥ 2, CCI ≥ 5, ECI ≥ 12.5. | |||||
| D—Multivariable analysis for hospital readmission | |||||
| Male sex | −0.443 | 0.219 | 0.64 | 0.42-0.99 | .04 |
| Heart rate | −0.014 | 0.006 | 0.99 | 0.97-0.99 | .02 |
| History of DM | 0.616 | 0.256 | 1.85 | 1.12-3.05 | .02 |
| Variables included in the model: Sex, Heart rate, BNP, Hypertension, CHF, CKD, liver disease, diabetes, statin therapy, anemia, organ transplantation, CCI ≥ 3. | |||||