Table 3.
Left ventricular diastolic and systolic parameters in 32 paediatric Loeys-Dietz syndrome patients
| Left ventricular functional parameters | TGFBR1 (n = 17) | TGFBR2 (n = 15) | P |
|---|---|---|---|
| Diastolic function | |||
| Mitral valve E-velocity (cm/s) | 83 (72.6-90.8) | 75 (72.0-89.5) | 0.850 |
| Mitral valve A-velocity (cm/s) | 43.8 ± 7.38 | 45.2 ± 12.7 | 0.733 |
| Mitral valve E/A ratio | 1.96 ± 0.56 | 1.97 ± 0.77 | 0.967 |
| Mitral valve E′-velocity (cm/s) | 16.3 ± 3.09 | 14.9 ± 3.52 | 0.279 |
| Mitral valve A′-velocity (cm/s) | 5.0 (4.2-7.0) | 6.5 (5.6-7.3) | 0.129 |
| Mitral valve E/E′ ratio | 4.81 (4.5-5.8) | 5.29 (4.8-5.5) | 0.451 |
| Isovolumetric relaxation time (ms) | 65.9 ± 15.4 | 57.9 ± 16.1 | 0.208 |
| Mitral valve deceleration time (ms) | 134 (116-169) | 143 (119.2-176.0) | 0.905 |
| Mitral valve A-wave time (ms) | 106.5 (96.5-148.5) | 106 (92.0-139.5) | 0.828 |
| Systolic function | |||
| Mitral valve S′-velocity (cm/s) | 10.0 (8.0-11.5) | 10.5 (8.1-12.1) | 0.380 |
| Ejection fraction (%) | 66.1 ± 5.41 | 67.7 ± 4.90 | 0.362 |
| Shortening fraction (%) | 35.1 (32.2-38.5) | 36.4 (33.6-39.4) | 0.484 |
Data are presented as mean ± standard deviation or median (interquartile range).