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(A) Minimal clinically important improvements observed for each impaired domain at 36-month follow-up. (B) Cumulative responder score at 36-month follow-up. *Statistical significant at p<0.05 level. CL-SCS, closed-loop SCS; MCID, minimal clinically important difference; ODI, Oswestry Disability Index; OL-SCS, open-loop SCS; POMS, Profile of Mood States; PSQI, Pittsburgh Sleep Quality Index; SCS, spinal cord stimulation; TMD, total mood disorder; VAS, Visual Analog Scale.
