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. 2024 Mar 25;73(6):1015–1024. doi: 10.1136/gutjnl-2023-330584

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© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Novel targets and therapies for acute-on-chronic liver failure. The Figure illustrates novel targets and therapies that are in early development and/or phases 1 and 2 trials for acute-on-chronic liver failure. G-CSF, granulocyte colony-stimulating factor; RIPK, receptor interacting protein kinase; TLR, toll-like receptor. Created with BioRender.com with publication licence.