Figure 3.

Comprehensive analysis of ECG data in logistic regression models predicting three categories of abnormal LVEF in childhood cancer survivors exposed to cardiotoxic cancer treatment. This figure illustrates the ECG data chosen through LASSO analysis and integrated into the binary variable 'abnormal ECG based on LASSO analysis' for each abnormal LVEF category. It also demonstrates the model’s discriminative capacity, encompassing clinical variables such as sex, age at diagnosis, age at ECG, and dosage of anthracycline, mitoxantrone and radiotherapy, alongside the selected ECG data. The provided diagnostic metrics relate to ruling out LVEF <45%. LASSO, least absolute shrinkage and selection operator; LBBB, left bundle branch block; LVEF, left ventricular ejection fraction.