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Throughput and depth are shown for several LC-MS/MS-based human proteomics investigations spanning the past decade. The number of unique human proteins identified are plotted against the total LC-MS/MS acquisition time. Squares denote fractionated experiments, and circles denote single-shot experiments. Note, these data report protein groups identified, not necessarily quantified. LC-MS/MS, liquid chromatography with tandem mass spectrometry.
