Antibacterial activity of the target compounds against the test bacteria at concentrations of 100 and 50 μg mL−1a.
Compounds | Inhibition rate (%) | |||||
---|---|---|---|---|---|---|
XOO | XAC | PSA | ||||
100 μg mL−1 | 50 μg mL−1 | 100 μg mL−1 | 50 μg mL−1 | 100 μg mL−1 | 50 μg mL−1 | |
6a | 18.93 ± 2.63 | 9.18 ± 1.71 | 34.41 ± 1.56 | 17.71 ± 3.36 | 16.53 ± 2.11 | 7.38 ± 2.20 |
6b | 40.21 ± 3.71 | 18.54 ± 2.59 | 13.13 ± 1.34 | 10.06 ± 0.78 | 11.24 ± 2.31 | 8.31 ± 1.12 |
6c | 26.40 ± 3.93 | 16.81 ± 3.41 | 79.33 ± 2.54 | 63.26 ± 1.56 | 8.49 ± 4.95 | 5.50 ± 4.30 |
6d | 14.88 ± 4.36 | 0 | 48.34 ± 2.87 | 43.56 ± 3.80 | 9.39 ± 1.49 | 0 |
6e | 22.04 ± 2.65 | 4.84 ± 2.04 | 58.89 ± 2.73 | 40.81 ± 2.16 | 12.10 ± 2.13 | 0 |
6f | 6.38 ± 1.25 | 1.47 ± 1.71 | 41.58 ± 3.88 | 20.16 ± 1.35 | 15.95 ± 3.49 | 7.91 ± 1.71 |
6g | 17.89 ± 3.43 | 8.49 ± 2.70 | 40.46 ± 1.25 | 26.64 ± 4.15 | 19.88 ± 1.94 | 11.05 ± 5.93 |
6h | 47.89 ± 0.53 | 46.16 ± 4.69 | 71.93 ± 3.26 | 33.32 ± 3.03 | 39.28 ± 0.66 | 8.70 ± 2.91 |
6i | 38.40 ± 2.05 | 17.98 ± 1.21 | 45.84 ± 3.28 | 22.13 ± 1.35 | 21.05 ± 2.49 | 10.83 ± 1.91 |
6j | 16.03 ± 2.72 | 1.60 ± 0.19 | 14.45 ± 4.05 | 10.59 ± 1.63 | 23.10 ± 3.44 | 0 |
6k | 54.27 ± 3.52 | 29.31 ± 1.11 | 18.46 ± 1.28 | 10.54 ± 0.95 | 28.94 ± 1.59 | 19.32 ± 1.71 |
6l | 56.43 ± 0.65 | 30.25 ± 0.81 | 40.58 ± 2.28 | 20.06 ± 1.35 | 45.73 ± 3.47 | 19.85 ± 0.97 |
6m | 36.64 ± 2.57 | 13.95 ± 4.42 | 51.85 ± 2.81 | 42.63 ± 3.03 | 36.34 ± 3.24 | 0 |
6n | 30.66 ± 3.01 | 11.95 ± 4.47 | 68.91 ± 0.27 | 50.46 ± 1.31 | 35.89 ± 3.79 | 0 |
6o | 15.48 ± 1.35 | 7.14 ± 3.41 | 52.99 ± 1.28 | 35.53 ± 1.38 | 17.08 ± 5.49 | 8.81 ± 1.15 |
6p | 37.46 ± 1.07 | 10.34 ± 3.41 | 85.76 ± 0.09 | 57.85 ± 2.41 | 28.59 ± 1.43 | 0 |
6q | 11.38 ± 0.35 | 7.73 ± 0.61 | 58.15 ± 2.18 | 34.73 ± 2.31 | 54.17 ± 3.49 | 24.91 ± 1.08 |
6r | 5.60 ± 1.75 | 0.85 ± 1.91 | 41.38 ± 1.28 | 22.13 ± 1.37 | 23.58 ± 1.09 | 10.16 ± 3.11 |
6s | 35.86 ± 1.25 | 17.34 ± 0.81 | 55.35 ± 1.18 | 36.13 ± 0.35 | 39.84 ± 2.38 | 19.91 ± 1.01 |
6t | 40.28 ± 3.10 | 19.18 ± 0.92 | 46.22 ± 1.71 | 42.77 ± 1.90 | 35.32 ± 3.91 | 5.05 ± 1.16 |
6u | 19.00 ± 4.35 | 13.73 ± 6.91 | 39.01 ± 8.98 | 37.03 ± 2.35 | 19.18 ± 5.49 | 4.41 ± 1.71 |
6v | 24.50 ± 1.04 | 19.72 ± 6.78 | 58.31 ± 1.72 | 43.93 ± 3.44 | 29.59 ± 1.32 | 10.61 ± 1.55 |
6w | 31.16 ± 0.33 | 15.63 ± 1.39 | 56.58 ± 1.26 | 32.55 ± 0.93 | 44.21 ± 1.56 | 20.22 ± 1.74 |
6x | 44.38 ± 1.23 | 31.09 ± 2.17 | 18.33 ± 1.06 | 11.54 ± 1.03 | 45.38 ± 2.06 | 22.56 ± 1.21 |
Thiadiazole copper | 61.36 ± 3.17 | 50.36 ± 3.72 | 76.59 ± 3.10 | 48.01 ± 2.33 | 92.67 ± 5.22 | 45.29 ± 3.25 |
Average of three replicates.