Figure 1.
Multimodal Imaging and Histopathologic Findings of FAVA
(A and B) Coronal and axial T2-weighted fat-suppressed magnetic resonance images showing an intramuscular vascular lesion with clearly interposed hyperintense fatty tissue, more than is usual in a normal venous malformation. (C) Sagittal T1-weighted magnetic resonance image with typical presentation of a fibro-adipose vascular anomaly (FAVA) called the black and white "salt and pepper pattern," caused by the neighboring fatty tissue and connective tissue. (D) Plain angiography image presents an extensive network of dilated, dysplastic venous channels forming the venous malformation part (arrow). (E) Overview tissue core in hematoxylin and eosin stain showing infiltrating vascularized fibro-adipose soft tissue (arrowhead) between skeletal muscle fibers and thick-walled venous vessels (asterisk) as well as several lymphoid aggregates (arrow). (F) CD34 immunostaining showing CD34 co-expression in the endothelium.