Determination of IC50 of compounds 7c, 13b, 17d and 18 on HepG2 cells.
Comp. | Conc. μmol mL−1 | IC50 μmol mL−1 | ||||
---|---|---|---|---|---|---|
0.01 | 0.1 | 1 | 10 | 100 | ||
7c (viability%) | 95.42% | 91.76% | 81.74% | 66.36% | 51.32% | 2.73 ± 0.25 |
13b (viability%) | 87.97% | 80.39% | 75.02% | 65.36% | 58.06% | 0.56 ± 0.03 |
17d (viability%) | 87.66% | 81.14% | 70.22% | 62.38% | 58.87% | 0.41 ± 0.01 |
18 (viability%) | 91.57% | 85.88% | 73.98% | 60.31% | 72.06% | 0.53 ± 0.05 |