Predicted ADMET properties of the tested compounds.

No	GI absorption	BBB permeant	Bioavailability score	CYP-substrate/inhibitor
				3A4	1A2	2C19	2C9	2D6
7b	Low	No	0.55	Yes	Yes	Yes	Yes	Yes
7c	Low	No	0.55	Yes	Yes	No	Yes	Yes
13b	Low	No	0.55	Yes	Yes	Yes	Yes	Yes
13c	Low	No	0.55	Yes	Yes	Yes	Yes	Yes
15c	High	No	0.55	Yes	Yes	Yes	Yes	Yes
17d	High	No	0.55	Yes	Yes	Yes	Yes	Yes
18	High	No	0.55	Yes	Yes	Yes	No	No
24	Low	No	0.55	Yes	Yes	No	Yes	Yes