Table 2.
Prevalence of adjudicated diagnoses and procedures in participants from the TODAY and SEARCH for Diabetes in Youth Studies. Rate is calculated per 10,000 person years.
| Type 1 Diabetes N=546 | Type 2 Diabetes N=644 | |||||
|---|---|---|---|---|---|---|
| Subjects with an event | Person Years | Rate | Subjects with an event | Person Years | Rate | |
| Ophthalmologic Diagnosis | ||||||
| PDR | 2 | 6428 | 3.11 | 20 | 8047 | 24.9 |
| Vitreous Hemorrhage | 1 | 6429 | 1.6 | 7 | 8071 | 8.7 |
| Macular Edema | 4 | 6425 | 6.2 | 17 | 8048 | 21.1 |
| Cataracts | 6 | 6408 | 9.4 | 10 | 8057 | 12.4 |
| Glaucoma | 2 | 6429 | 3.1 | 6 | 8062 | 7.4 |
| Blindness | 1 | 6429 | 1.6 | 1 | 8078 | 1.2 |
| Any Ophthalmologic event | 7 | 6405 | 10.9 | 32 | 8008 | 40.0 |
| Kidney Diagnosis | ||||||
| Chronic Kidney Disease | 0 | 6431 | 0.0 | 5 | 8062 | 6.2 |
| End-stage Kidney Disease | 0 | 6431 | 0.0 | 4 | 8070 | 5.0 |
| Any Kidney Diagnosis | 0 | 6431 | 0.0 | 5 | 8062 | 6.2 |
| Neuropathy Diagnosis | ||||||
| Peripheral Neuropathy | 2 | 6426 | 3.1 | 10 | 8055 | 12.4 |
| Autonomic Neuropathy | 5 | 6423 | 7.8 | 7 | 8060 | 8.7 |
| Mononeuropathy | 0 | 6431 | 0.0 | 1 | 8074 | 1.2 |
| Any Neuropathy event | 7 | 6334 | 11.1 | 17 | 8022 | 21.2 |
| Any Microvascular event | 14 | 6405 | 21.9 | 45 | 7958 | 56.5 |
| Cardiac Diagnosis | ||||||
| Arrhythmia | 1 | 6428 | 1.6 | 10 | 8038 | 12.4 |
| Myocardial Infarction | 1 | 6424 | 1.6 | 4 | 8073 | 5.0 |
| CAD without MI | 0 | 6431 | 0.0 | 3 | 8073 | 3.7 |
| CHF | 0 | 6431 | 0.0 | 6 | 8068 | 7.4 |
| LV systolic dysfunction | 0 | 6431 | 0.0 | 6 | 8067 | 7.4 |
| Any Cardiac Event | 2 | 6422 | 3.1 | 17 | 8026 | 21.2 |
| Vascular Diagnosis or Procedures | ||||||
| Peripheral Artery Disease | 0 | 6431 | 0.0 | 1 | 8077 | 1.2 |
| Renal Artery Disease | 0 | 6431 | 0.0 | 0 | 8078 | 0.0 |
| Amputation | 0 | 6431 | 0.0 | 2 | 8074 | 2.5 |
| Arterial Bypass or Stent Placement | 0 | 6431 | 0.0 | 0 | 8078 | 0.0 |
| DVT | 2 | 6410 | 3.1 | 6 | 8059 | 7.5 |
| Any Vascular Event or procedure | 2 | 6410 | 3.1 | 8 | 8054 | 9.9 |
| Cerebrovascular Diagnosis | ||||||
| Stroke | 1 | 6425 | 1.6 | 3 | 8070 | 3.7 |
| Transient Ischemic Attack | 0 | 6431 | 0.0 | 1 | 8074 | 1.2 |
| Cerebrovascular Disease without stroke or TIA | 0 | 6431 | 0.0 | 0 | 8078 | 0.0 |
| Any Cerebrovascular Event | 1 | 6425 | 1.6 | 4 | 8065 | 5.0 |
| Any Macrovascular event | 5 | 6395 | 7.8 | 26 | 7995 | 32.5 |
| Any Micro/Macrovascular event | 19 | 6370 | 29.8 | 65 | 7894 | 82.3 |
| Gastrointestinal Diagnosis | ||||||
| Pancreatitis | 4 | 6410 | 6.2 | 9 | 8046 | 11.2 |
| Gallbladder Disease | 6 | 6417 | 9.4 | 28 | 7971 | 35.1 |
| Cirrhosis | 0 | 6431 | 0.0 | 0 | 8078 | 0.0 |
| Any Gastrointestinal Event | 10 | 6396 | 15.6 | 34 | 7949 | 42.8 |