Table 3.

Univariate Cox proportional hazards models for micro- and macrovascular clinical events in SEARCH participants with Type 1 Diabetes and Type 2 Diabetes.

	Events of Interest
	Micro-vascular Events			Macro-Vascular Events
	HR	95% CI	p-value	HR	95% CI	p-value
Type 1 Diabetes
Sex: Female (ref=Male)	5.0	(1.1, 22.4)	0.04	0.6	(0.1, 3.3)	0.5
Race: Other (ref=NHW)	2.4	(0.8, 7.0)	0.14	1.0	(0.2, 6.1)	1.0
Age at diagnosis (per 1 year increase)	1.2	(1.0, 1.3)	0.01	1.1	(0.9, 1.4)	0.3
HbA1c (per 1% increase)	1.3	(1.1, 1.6)	0.001	1.0	(0.7, 1.5)	0.9
MAP (per 10 mmHg increase)	1.9	(1.2, 2.9)	0.01	0.8	(0.3, 2.3)	0.7
Ln(Triglycerides)	1.8	(0.6, 5.0)	0.3	0.9	(0.2, 5.0)	0.9
LDL (per 10 mg/dL increase)	1.1	(0.9, 1.3)	0.4	1.0	(0.7, 1.3)	0.8
BMI (per 5 unit increase)	0.7	(0.4, 1.3)	0.3	0.8	(0.3, 1.9)	0.6
Number of events	14			5
Type 2 Diabetes
Sex: Female (ref=Male)	0.8	(0.4, 1.5)	0.5	0.6	(0.3, 1.4)	0.2
Race (ref=NHW)
Black	1.0	(0.4, 2.3)	0.6	1.7	(0.6, 5.3)	0.4
Other	1.4	((0.6, 3.1)		1.0	(0.3, 3.3)
Age at diagnosis (per 1 year increase)	1.0	(0.9, 1.2)	0.9	1.1	(0.9, 1.3)	0.4
HbA1c (per 1% increase)	1.0	(0.9, 1.1)	0.7	1.1	(0.9, 1.2)	0.3
MAP (per 10 mmHg increase)	1.4	(1.1, 1.7)	0.0007	1.5	(1.2, 1. 8)	0.0009
Ln (Triglycerides)	0.8	(0.5, 1.3)	0.4	1.2	(0.7, 2.1)	0.5
LDL (per 10 mg/dL increase)	1.0	(0.9, 1.1)	0.7	0.9	(0.8, 1.0)	0.2
BMI (per 5 unit increase)	0.7	(0.6, 0.9)	0.007	1.1	(0.9, 1.3)	0.4
Study: TODAY (ref=SEARCH)	2.3	(0.7, 7.6)	0.2	1.5	(0.4, 4.9)	0.5
Number of events	45			26