Table 2.
Means (standard deviations) for QOL domain scores at each timepoint by age group.
| Timepoint | Age Group | n | Physical Function | Social Function | Role Function | Emotional Function | Cognitive Function | Global QOL |
|---|---|---|---|---|---|---|---|---|
| Baseline (Month 0) |
18–39 | 56 | 92.36 (14.02)a | 71.73 (29.11)a | 80.30 (29.59)a | 65.87 (24.99)a | 83.93 (21.55) | 68.75 (21.16)a |
| 40–49 | 145 | 86.90 (18.35)b | 67.24 (30.90) | 73.10 (30.06) | 63.68 (26.96)a | 81.61 (23.55) | 63.22 (22.00)a | |
| 50–64 | 492 | 85.13 (20.55)b | 71.87 (29.32) | 75.12 (30.90) | 63.84 (27.01)a | 82.11 (23.03) | 62.61 (24.02)a,b | |
| 65+ | 549 | 80.43 (21.91)a,b | 76.71 (27.45) | 74.47 (30.78) | 70.17 (26.15)a | 84.49 (19.60) | 62.10 (23.23)a,b | |
| Month 3 | 18–39 | 37 | 86.13 (14.35)a | 66.67 (29.13)a | 68.47 (32.58)a | 76.35 (24.57) | 81.08 (22.62) | 65.99 (20.54)a |
| 40–49 | 110 | 81.90 (21.47)a | 66.06 (30.37) | 65.15 (33.30) | 73.18 (24.35) | 80.45 (24.20) | 63.56 (23.05)a | |
| 50–64 | 374 | 79.68 (20.66)a,b | 66.44 (30.74) | 64.26 (33.34) | 70.57 (25.45) | 81.42 (22.27) | 63.56 (20.41)a | |
| 65+ | 438 | 77.84 (21.05)a,b | 77.55 (26.55)b | 71.78 (31.21) | 80.77 (19.92) | 86.27 (18.30) | 65.79 (20.41)a | |
| Month 6 | 18–39 | 43 | 84.65 (16.94)a | 72.48 (29.07)a | 71.71 (31.82)a | 69.96 (25.01)a | 76.74 (24.70) | 68.80 (20.98)a |
| 40–49 | 97 | 83.52 (17.47) | 67.87 (29.29) | 68.73 (32.65) | 68.73 (26.76)a | 74.57 (26.25)a | 65.72 (20.41)a | |
| 50–64 | 345 | 80.36 (21.30)a | 69.23 (29.97) | 67.30 (31.61) | 69.58 (25.25)a | 80.38 (22.52) | 63.52 (21.53)a | |
| 65+ | 380 | 76.70 (20.65)a,b | 73.88 (28.32) | 72.27 (29.96) | 76.52 (23.43) | 82.50 (19.39) | 64.37 (21.29)a | |
| Month 12 | 18–39 | 39 | 88.38 (15.43)a | 75.64 (29.58)a | 73.08 (33.47)a | 73.72 (22.90) | 81.20 (23.63) | 73.50 (18.02) |
| 40–49 | 83 | 83.94 (21.36) | 69.31 (31.37) | 72.69 (32.36) | 68.60 (26.78)a | 75.61 (25.42) | 66.77 (23.55) | |
| 50–64 | 292 | 84.97 (19.29) | 77.68 (26.58) | 77.55 (28.80) | 75.29 (22.25) | 80.46 (22.43) | 69.45 (20.56) | |
| 65+ | 340 | 82.19 (20.87)a,b | 82.50 (25.00) | 80.42 (27.44) | 81.44 (21.02) | 84.76 (19.01) | 71.29 (20.25) |
Note: QOL, quality of life.
a
Average score was below age-relevant threshold indicating clinically meaningful QOL dysfunctional/impairment.
b
Average score is significantly different from YA average score based on independent samples t-test at the given timepoint with p<0.05.