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. Author manuscript; available in PMC: 2024 Jul 19.
Published in final edited form as: Support Care Cancer. 2024 Apr 19;32(5):298. doi: 10.1007/s00520-024-08511-5

Table 3.

Results of mixed-effect models examining changes in average QOL domain scores by age group over time.

Physical
Function
Social
Function
Role
Function
Emotional
Function
Cognitive
Function
Global
QOL
(Intercept) 89.44 (84.69–94.19)*** 68.98 (62.47–75.48)*** 77.00 (69.90–84.10)*** 68.65 (63.07–74.24)*** 82.20 (77.30–87.10)*** 66.93 (61.98–71.88)***
Time (vs. 0, baseline) −0.17 (−0.69–0.35) 0.56 (−0.21–1.34) −0.46 (−1.34–0.41) 0.46 (−0.17–1.08) −0.30 (−0.84–0.24) 0.46 (−0.13–1.06)
Age Group (vs. YA)
  40–49 −3.09 (−8.68–2.50) −0.93 (−8.60–6.74) −5.35 (−13.71–3.00) −0.60 (−7.20–5.99) −0.37 (−6.15–5.42) −2.58 (−8.41–3.26)
  50–64 −6.60 (−11.62-−1.59)** 0.42 (−6.46–7.29) −6.62 (−14.13–0.88) −3.04 (−8.95–2.87) −0.74 (−5.93–4.45) −4.65 (−9.88–0.58)
  65+ −10.44 (−15.43-−5.45)*** 6.96 (0.12–13.80)* −4.27 (−11.73–3.19) 4.72 (−1.16–10.60) 2.40 (−2.76–7.56) −4.38 (−9.58–0.82)
Time x Age Group
  Time x 40–49 −0.09 (−0.71–0.52) −0.52 (−1.45–0.41) 0.42 (−0.63–1.46) −0.24 (−0.99–0.50) −0.19 (−0.84–0.45) −0.23 (−0.94–0.48)
  Time x 50–64 0.06 (−0.49–0.61) −0.18 (−1.01–0.64) 0.61 (−0.32–1.53) 0.29 (−0.37–0.95) 0.1 (−0.47–0.67) −0.03 (−0.66–0.59)
  Time x 65+ 0.14 (−0.40–0.68) −0.27 (−1.09–0.54) 0.78 (−0.14–1.70) 0.19 (−0.47–0.84) 0.23 (−0.33–0.80) 0.12 (−0.50–0.74)

N (ID) 1586 1586 1587 1588 1588 1589
AIC 32816.43 36408.23 34150.43 33139.80 35636.79 33547.91
R2 (fixed) 0.02 0.00 0.03 0.01 0.02 0.01
R2 (total) 0.58 0.42 0.57 0.58 0.48 0.47

Note: Each column reflects a separate mixed-effect model. YA, young adult aged 18–39; QOL, quality of life.

*

p<0.05

**

p<0.01

***

p<0.001.