Table 4.

Results of logistic regression models with mixed effects examining changes in the proportion of participants with clinically meaningful QOL domain scores by age group over time.

	Physical Function	Social Function	Role Function	Emotional Function	Cognitive Function	Global QOL
(Intercept)	1.01 (0.52–1.96)	3.30 (1.71–6.38)***	0.97 (0.53–1.77)	1.08 (0.55–2.10)	0.36 (0.17–0.75)**	1.19 (0.65–2.20)
Time (vs. 0, baseline)	1.02 (0.93–1.11)	0.90 (0.83–0.98)*	1.03 (0.95–1.11)	0.95 (0.87–1.04)	1.00 (0.92–1.10)	0.97 (0.90–1.05)
Age Group (vs. YA)
40–49	0.42 (0.19–0.93)*	0.13 (0.06–0.29)***	0.36 (0.18–0.75)**	0.89 (0.41–1.95)	0.99 (0.41–2.35)	0.50 (0.24–1.03)
50–64	0.55 (0.27–1.12)	0.10 (0.05–0.21)***	0.41 (0.22–0.78)**	1.11 (0.55–2.24)	1.09 (0.50–2.38)	0.63 (0.33–1.20)
65+	0.83 (0.41–1.68)	0.07 (0.04–0.15)***	0.32 (0.17–0.61)***	0.54 (0.27–1.10)	0.72 (0.33–1.56)	0.71 (0.38–1.36)
Time x Age Group
Time x 40–49	1.00 (0.90–1.10)	1.09 (0.99–1.21)	0.96 (0.87–1.06)	1.05 (0.94–1.16)	1.07 (0.96–1.20)	0.99 (0.90–1.10)
Time x 50–64	0.99 (0.91–1.09)	1.09 (0.99–1.19)	0.96 (0.88–1.04)	0.98 (0.90–1.08)	1.01 (0.92–1.12)	0.98 (0.90–1.07)
Time x 65+	0.98 (0.89–1.07)	1.07 (0.98–1.18)	0.95 (0.87–1.04)	1.00 (0.91–1.1.00)	0.97 (0.88–1.07)	0.97 (0.89–1.05)
N (ID)	1586	1588	1586	1587	1588	1589
AIC	4746.33	4016.57	4246.76	4683.51	4128.66	4799.69
R2 (fixed)	0.01	0.04	0.02	0.02	0.02	0.01
R2 (total)	0.50	0.45	0.41	0.50	0.55	0.42

Note: Each column reflects a separate logistic regression model with mixed-effects. YA, young adult aged 18–39; QOL, quality of life.

^*p<0.05

^**p<0.01

^***p<0.001.