Figure 2.
Androgen receptor expression in immune cells. Innate immune cells such as neutrophils, monocytes and macrophages express AR. AR is predominantly expressed in the cytoplasm with some evidence for membrane expression in macrophage subsets. T and B lymphocytes of the adaptive immune system are also AR positive with AR detected in the cytoplasm and membrane of T cells and cytoplasm of B cell progenitors (Milewich et al. 1983, Kovacs & Olsen 1987, Viselli et al. 1997, Benten et al. 1999a, Mantalaris et al. 2001, Wunderlich et al. 2002, Liu et al. 2004, Sinha-Hikim et al. 2004, Liu et al. 2005, Ahmadi & McCruden 2006, Bolego et al. 2013, Bizzaro et al. 2018, Rubinow et al. 2018, Lee et al. 2019, Markman et al. 2020, McCrohon et al. 2000, Campesi et al. 2012). •, mouse; °, human; +, mouse and human. Created with BioRender.com.