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. 2024 May 20;10(3):00007-2024. doi: 10.1183/23120541.00007-2024

TABLE 3.

Summary of dog training on 24 Getxent tubes used in gas chromatography-mass spectrometry (GC-MS) analysis

Dog 1 Dog 2 Dog 3 Total (%) Mean (Q3–Q1)
Total runs on specified positive gargle samples (n=14) 99 94 71 264 (100) 20 (23)
Total runs with false positives 4 1 1 6 (2.3) NA
Total runs on specified negative gargle samples (n=10) 55 60 47 162 (100) 16 (16)
Total runs with false negatives 6 2 4 12 (7.4) NA

Using the discrepancy matrix, samples with a failure rate of dog alert above 15% were considered negative for the purpose of this analysis. Altogether, the model correctly classified 68% of the samples with F1 and Matthew's correlation coefficient scores of 0.69 and 0.37, respectively, considered to be a good concordance between the two methods (table 4). Individually, the Kappa agreement between the dogs and GC-MS was moderate: 0.503 for dog A, 0.510 for dog B and 0.412 for dog C.