Figure 5.

Chromosomal location of human and mouse Sox8. (A) Recombination analysis of mouse interspecific backcrosses. Filled squares represent the M.musculus Sox8 allele, open squares represent the M.spretus allele, with numbers below representing the number of backcross progeny mice typed for each combination. Sox8 also co-segregated with the anonymous marker locus D17Mit43. ND is used when no data were recorded for D17Mit100. (B) Comparative maps of mouse chromosome 17 (Mmu17) and human chromosome 16 (Hsa16). The positions of conserved syntenic genes are represented along the central axis with Sox8 positioned between Mcpt6 (human TPS2) and Axin. The dashed line represents the orientation on the chromosome. Mouse anonymous marker loci are shown to the left of chromosome Mmu17. Ideogram band labels are positioned to the right of human chromosome 16.