Table 2.
Median (interquartile range) pre- and post-sedation values of echocardiographic variables, blood pressure and heart rate in 50 healthy cats sedated with dexmedetomidine and buprenorphine
| Pre-sedation | Post-sedation | Change | P value | |
|---|---|---|---|---|
| LVIDd (cm) | 1.62 (1.49–1.74) | 1.67 (1.53–1.77) | –0.08 (–0.17 to 0.05) | 0.015 |
| LVIDs (cm) | 0.87 (0.81–1.06) | 1.15 (0.98–1.24) | –0.25 (−0.38 to −0.08) | <0.0001 |
| IVSd (cm) | 0.36 (0.32–0.41) | 0.37 (0.33–0.39) | 0.00 (–0.04 to 0.04) | 0.75 |
| IVSs (cm) | 0.50 (0.45–0.58) | 0.49 (0.44–0.55) | 0.01 (–0.03 to 0.10) | 0.089 |
| Ao Vmax (m/s) | 0.90 (0.85–0.98) | 0.42 (0.36–0.55) | 0.48 (0.37–0.57) | <0.0001 |
| PA Vmax (m/s) | 0.86 (0.76–0.96) | 0.41 (0.37–0.56) | 0.43 (0.31–0.5) | <0.0001 |
| PA AT (ms) | 0.53 (0.41–0.58) | 0.48 (0.41–0.52) | 0.02 (–0.05 to 0.1) | 0.088 |
| PA DT (ms) | 0.54 (0.44–0.64) | 0.9 (0.69–1.21) | –0.38 (−0.54 to −0.22) | <0.0001 |
| PA AT/DT | 0.99 (0.86–1.06) | 0.54 (0.42–0.68) | 0.43 (0.31–0.56) | <0.0001 |
| Left atrium (cm) | 1.05 (1.00–1.10) | 1.10 (1.00–1.13) | 0.00 (–0.10 to 0.00) | 0.022 |
| Aorta (cm) | 0.90 (0.90–1.00) | 0.90 (0.90–1.00) | 0.00 (–0.10 to 0.00) | 0.52 |
| LA/Ao | 1.11 (1.00–1.22) | 1.11 (1.10–1.22) | 0.00 (–0.11 to 0.00) | 0.37 |
| FS (%) | 44.0 (37.4–49.9) | 30.4 (26.1–33.1) | 12.6 (7.1–19.9) | <0.0001 |
| RVIDd (cm) | 0.20 (0.19–0.27) | 0.25 (0.20–0.35) | –0.04 (–0.12 to 0.01) | 0.002 |
| LVPWd (cm) | 0.39 (0.34–0.42) | 0.38 (0.35–0.42) | 0 (–0.03 to 0.04) | 0.58 |
| LVPWs (cm) | 0.56 (0.49–0.65) | 0.57 (0.49–0.61) | 0.01 (–0.04 to 0.06) | 0.82 |
| HR (BP device) (bpm) | 164 (144–186) | 90 (80–100) | 72 (56–91) | <0.0001 |
| HR (echo) (bpm) | 189 (161–220) | 93 (80–100) | 90 (70–122) | <0.0001 |
| SBP (mmHg) | 156 (141–171) | 174 (158–185) | –15.5 (−31.5 to −0.25) | 0.0006 |
| DBP (mmHg) | 101 (87–109) | 120 (105–131) | –14.5 (−35 to −2.75) | <0.0001 |
| MAP (mmHg) | 118 (111–130) | 137 (121–148) | –15 (−30.5 to −5.75) | <0.0001 |
Median change is displayed as the post-sedation value subtracted from the pre-sedation value
LVIDd = left ventricular internal diameter at end-diastole; LVIDs = left ventricular internal diameter at end-systole; IVSd = interventricular septum at end-diastole; IVSs = interventricular septum at end-systole; Ao Vmax = maximum velocity in aorta; PA Vmax = pulmonary artery maximum velocity; PA AT = pulmonary artery acceleration time; PA DT = pulmonary artery deceleration time; PA AT/DT = pulmonary artery acceleration time/deceleration time; LA/Ao = left atrial to aortic root ratio; FS = fractional shortening; RVIDd = right ventricular dimension at end-diastole; LVPWd = left ventricular posterior wall at end-diastole; LVPWs = left ventricular posterior wall at end-systole; HR (BP device) = blood pressure device-obtained heart rate; HR (echo) = echocardiographically obtained heart rate; SBP = systolic blood pressure; DBP = diastolic blood pressure; MAP = mean arterial pressure