Table 3.

Association between pre-sedation value and absolute and relative change in the same variable post-sedation for each echocardiographic, blood pressure and heart rate variable in 50 healthy cats sedated with dexmedetomidine and buprenorphine

	Absolute change		Relative change
	R2 value	P value	R2− value	P value
LVIDd	0.28	<0.0001	0.33	<0.0001
LVIDs	0.20	0.001	0.31	<0.0001
IVSd	0.16	0.004	0.18	0.002
IVSs	0.49	<0.0001	0.39	<0.0001
Ao Vmax	0.33	<0.0001	0.09	0.035
PA Vmax	0.31	<0.0001	–	0.22
PA AT	0.30	<0.0001	0.33	<0.0001
PA DT	–	0.28	–	0.28
PA AT/DT	0.26	0.0002	–	0.07
Left atrial diameter	0.36	<0.001	0.37	<0.0001
Aortic diameter	0.35	<0.0001	0.34	<0.0001
LA/Ao	0.39	<0.0001	0.40	<0.0001
FS	0.50	<0.0001	0.30	<0.0001
RVIDd	0.22	0.0005	0.27	<0.0001
LVPWd	0.19	0.002	0.17	0.003
LVPWs	0.55	<0.0001	0.50	<0.0001
HR (BP device)	0.44	<0.0001	0.11	0.02
HR (echo)	0.76	<0.0001	0.37	<0.0001
SBP	0.50	<0.0001	0.53	<0.0001
DBP	0.35	<0.0001	0.40	<0.0001
MAP	0.24	0.0003	0.29	<0.0001

LVIDd = left ventricular internal diameter at end-diastole; LVIDs = left ventricular internal diameter at end-systole; IVSd = interventricular septum at end-diastole; IVSs = interventricular septum at end-systole; Ao V_max = maximum velocity in aorta; PA V_max = pulmonary artery maximum velocity; PA AT = pulmonary artery acceleration time; PA DT = pulmonary artery deceleration time; PA AT/DT = pulmonary artery acceleration time/deceleration time; LA/Ao = left atrial to aortic root ratio; FS = fractional shortening; RVIDd = right ventricular dimension at end-diastole; LVPWd = left ventricular posterior wall at end-diastole; LVPWs = left ventricular posterior wall at end-systole; HR (BP device) = blood pressure device–obtained heart rate; HR (echo) = echocardiographically obtained heart rate; SBP = systolic blood pressure; DBP = diastolic blood pressure; MAP = mean arterial pressure