Figure 3.

Progression-free interval comparison between patients receiving one or two previous protocols before beginning lomustine versus patients receiving three or four previous protocols before beginning lomustine. Cats that received 3–4 previous chemotherapy protocols were 3.6 times as likely to have disease progression compared to the cats that received 1–2 previous protocols (P = 0.02). The median PFI for cats that received 1–2 protocols was 31 days versus 77.5 days for cases receiving 3–4 previous protocols. However, if the cats survived past the median point, the cases with 1–2 previous protocols went on to stay on the protocol longer