Table 1.
VCOG-CTCAE values used in this study
| Normal range a | Grade 1 | Grade 2 | Grade 3 | Grade 4 | |
|---|---|---|---|---|---|
| Platelets 103/µl | 200–500 | 100–<200 | 50–99 | 25–49 | <25 |
| BUN mg/dl | 14–36 | >36–54 | >54–72 | >72–108 | >108 |
| Creatinine mg/dl | 0.6–2.4 | >2.4–3.6 | >3.6–4.8 | >4.8–7.2 | >7.2 |
| ALT IU/l | 10–100 | >100–125 | >125–150 | >150–200 | >200 |
| HCT% b | 29–48 | 25–29 | 20–<25 | 15–<20 | <15 |
a
Normal ranges obtained for BUN, Creat, and ALT, from Antech Diagnostics Laboratory, Irvine, CA, USA
b
Modified from VCOG-CTCAE, because the HCT was documented in the medical records of our cases rather than the PCV used to determine grades of anemia in the VCOG article
c
Normal range obtained for HCT and PLT, from Heska HemaTrue Veterinary Hematology Analyzer, which is the in-house CBC machine used at both locations of the Veterinary Cancer Group where data was collected for this study
ALT = alanine transaminase, BUN = blood urea nitrogen, Creat = creatinine, HCT = hematocrit, PCV = packed cell volume, PLT = platelets