Table 4.
Days | Treatment groups |
P values |
||||
---|---|---|---|---|---|---|
CsA % of events (number of cats) | Control % of events (number of cats) | MP % of events (number of cats) | CsA vs control | CsA vs MP | Control vs MP | |
7 days before treatment | 0 (0) | 0 (0) | 0 (0) | 1 | 1 | 1 |
1–7 | 1.8 (1) | 0 (0) | 5.4 (3) | 1 | 0.6182 | 0.2462 |
8–14 | 3.6 (2) | 6.1 (2) | 19.6 (2) | 0.6624 | 0.0155 | 0.0486 |
15–21 | 5.4 (1) | 0 (0) | 16.1 (3) | 0.2462 | 0.1239 | 0.0032 |
22–28 | 8.9 (3) | 0 (0) | 17.9 (2) | 0.0593 | 0.2668 | 0.0015 |
29–35 | 0 (0) | 0 (0) | 12.5 (2) | 1 | 0.0128 | 0.0140 |
36–42 | 0 (0) | 0 (0) | 5.4 (2) | 1 | 0.2432 | 0.2462 |
Overall* | 3.3 (3) | 1.02 (2) | 12.8 (3) | 0.0622 | <0.0001 | <0.0001 |
Statistical comparisons made by Fisher’s exact test with significance defined as P <0.05. Statistically significant differences are shown in bold
Overall test run on data from days 1–42 (pretreatment data [days −6 to 0] were excluded from overall analysis)
CsA = ciclosporin (cyclosporine) A given at 7.0 mg/kg, PO, daily on days 0–42; MP = methylprednisolone at 5 mg/kg, IM, days 0 and 21; control cats were administered corn syrup, PO, daily on days 0–42