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. Author manuscript; available in PMC: 2024 May 20.
Published in final edited form as: J Am Coll Cardiol. 2023 Nov 30;83(1):109–279. doi: 10.1016/j.jacc.2023.08.017

TABLE 14.

Situations in Which Long-Term Anticoagulation Is Contraindicated and Situations When It Remains Reasonable

Long-Term Anticoagulation
Contraindicated
Long-Term Anticoagulation
Is Still Reasonable
  • Severe bleeding due to a nonreversible cause involving the gastrointestinal, pulmonary, or genitourinary systems

  • Spontaneous intracranial/intraspinal bleeding due to a nonreversible cause

  • Serious bleeding related to recurrent falls when cause of falls is not felt to be treatable

  • Bleeding involving the gastrointestinal, pulmonary, or genitourinary systems that is treatable

  • Bleeding related to isolated trauma

  • Bleeding related to procedural complications