COR	LOE	RECOMMENDATIONS
1	B-NR	1. In patients with newly diagnosed AF, a transthoracic echocardiogram1-4 to assess cardiac structure, laboratory testing to include a complete blood count, metabolic panel, and thyroid function,5-7 and when clinical suspicion exists, targeted testing to assess for other medical conditions associated with AF are recommended to determine stroke and bleeding risk factors, as well as underlying conditions that will guide further management.
3: No benefit	B-NR	2. In patients with newly diagnosed AF, protocolized testing for ischemia, acute coronary syndrome (ACS), and pulmonary embolism (PE) should not routinely be performed to assess the etiology of AF unless there are additional signs or symptoms to indicate those disorders.8-10