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. Author manuscript; available in PMC: 2024 May 20.
Published in final edited form as: J Am Coll Cardiol. 2023 Nov 30;83(1):109–279. doi: 10.1016/j.jacc.2023.08.017
COR LOE RECOMMENDATIONS
1 A 1. In patients with AF and an increased risk for stroke who undergo PCI, DOACs are preferred over VKAs in combination with APT to reduce the risk of clinically relevant bleeding.1-5
1 A 2. In most patients with AF who take oral anticoagulation and undergo PCI, early discontinuation of aspirin (1-4 wk) and continuation of dual antithrombotic therapy with OAC and a P2Y12 inhibitor is preferred over triple therapy (OAC, P2Y12 inhibitor, and aspirin) to reduce the risk of clinically relevant bleeding.1-4,6