COR	LOE	RECOMMENDATIONS
1	A	1. In patients with symptomatic AF in whom antiarrhythmic drugs have been ineffective, contraindicated, not tolerated or not preferred, and continued rhythm control is desired, catheter ablation is useful to improve symptoms.1-10
1	A	2. In selected patients (generally younger with few comorbidities) with symptomatic paroxysmal AF in whom rhythm control is desired, catheter ablation is useful as first-line therapy to improve symptoms and reduce progression to persistent AF.11-16
1	A	3. In patients with symptomatic or clinically significant AFL, catheter ablation is useful for improving symptoms.17-19
2a	B-NR	4. In patients who are undergoing ablation for AF, ablation of additional clinically significant supraventricular arrhythmias can be useful to reduce the likelihood of future arrhythmia.17,18,20-27
2a	B-R	5. In patients (other than younger with few comorbidities) with symptomatic paroxysmal or persistent AF who are being managed with a rhythm-control strategy, catheter ablation as first-line therapy can be useful to improve symptoms.11-13,28
Cost Value Statement: Intermediate	B-R	6. Catheter ablation for symptomatic AF provides intermediate economic value compared with antiarrhythmic drug therapy.29,30
2b	B-NR	7. In selected* patients with asymptomatic or minimally symptomatic AF, catheter ablation may be useful for reducing progression of AF and its associated complications.31-39

^*Younger patients with few comorbidities and a moderate to high burden of AF or persistent AF and AFL.