Table 2.
Predictor | Yale health system Beta (SE), OR (95% CI), P-value |
UK Biobank cohort Beta (SE), OR (95% CI), P-value |
---|---|---|
Age (per 10 years) | 0.14 (0.01), 1.15 (1.13–1.17), P < 0.001 | 0.05 (0.05), 1.05 (0.95–1.16), P = 0.34 |
Female (sex) | −1.64 (0.02), 0.19 (0.19–0.20), P < 0.001 | −0.49 (0.08), 0.61 (0.52–0.72), P < 0.001 |
Hispanic ethnicity | 0.03 (0.04), 1.03 (0.96–1.11), P = 0.392 | — |
Race: Asian (vs. White) | −0.12 (0.06), 0.89 (0.80–0.99), P = 0.038 | 0.35 (0.23), 1.42 (0.91–2.26), P = 0.13 |
Race: Black (vs. White) | −0.23 (0.03), 0.79 (0.75–0.83), P < 0.001 | −0.01 (0.32), 0.99 (0.54–1.88), P = 0.98 |
BMI (per 10 kg/m2) | 0.27 (0.02), 1.31 (1.27–1.35), P < 0.001 | 1.13 (1.07), 3.09 (0.55–57.91), P = 0.29 |
Total cholesterol (per 10 mg/dL) | −0.02 (0.00), 0.98 (0.97–0.98), P < 0.001 | 0.02 (0.01), 1.02 (1.00–1.04), P = 0.12 |
HDL (per 10 mg/dL) | 0.03 (0.01), 1.03 (1.01–1.04), P < 0.001 | 0.06 (0.04), 1.06 (0.99–1.14), P = 0.08 |
Hypertension | −1.16 (0.02), 0.31 (0.30–0.33), P < 0.001 | −0.09 (0.09), 0.92 (0.78–1.09), P = 0.32 |
Diabetes mellitus | −2.34 (0.02), 0.10 (0.09–0.10), P < 0.001 | −1.3 (0.11), 0.27 (0.22–0.34), P < 0.001 |
Ischaemic heart disease history | 0.40 (0.03), 1.49 (1.40–1.59), P < 0.001 | 0.00 (0.09), 1.00 (0.85–1.19), P = 0.97 |
Chronic kidney disease | 0.19 (0.05), 1.21 (1.09-1.34), P < 0.001 | −0.21 (0.15), 0.81 (0.60–1.10), P = 0.17 |
Anti-platelet use | −0.47 (0.02), 0.63 (0.60–0.65), P < 0.001 | −0.42 (0.10), 0.66 (0.55–0.79), P < 0.001 |
Statin use | −0.19 (0.02), 0.83 (0.80–0.86), P < 0.001 | 0.38 (0.10), 1.46 (1.20–1.79), P < 0.001 |
Beta-blocker use | −1.91 (0.02), 0.15 (0.14–0.15), P < 0.001 | −1.06 (0.10), 0.35 (0.29–0.42), P < 0.001 |
Active smoking | −0.62 (0.12), 0.54 (0.42–0.69), P < 0.001 | −0.29 (0.12), 0.75 (0.59–0.95), P = 0.02 |
Former smoking | −0.38 (0.04), 0.68 (0.63–0.74), P < 0.001 | −0.24 (0.08), 0.78 (0.67–0.92), P = 0.003 |
BMI, body mass index; CI, confidence interval; OR, odds ratio; SE, standard error.