Table VI.
Multivariable regression model of factors associated with inpatient costs in children with CCHD by age*
| Factors | 0-Year 1 (n = 1434) |
Years 2-5 (n = 943) |
Years 6-10 (n = 432) |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total cohort |
Survivors only |
Total cohort |
Survivors only |
Total cohort |
Survivors only |
|||||||
| Marginal Δ (Coeff)† | P value | Marginal Δ (Coeff)† | P value | Marginal Δ | P value | Marginal Δ | P value | Marginal Δ | P value | Marginal Δ | P value | |
| Prenatal diagnosis | $20 869 (0.192) | .008 | $2517 (0.025) | .72 | $2348 | .57 | $1808 | .61 | $2518 | .42 | $4249 | .19 |
| Additional major CHD | $30 313 (0.278) | .013 | $21 206 (0.21) | .06 | $14 225 | .02 | $14 280 | .01 | $11 786 | .008 | $9123 | .03 |
| Year of birth | $1704 (0.016) | .043 | $991 (0.010) | .18 | −$1236 | .02 | −$697 | .14 | −$734 | .22 | −$732 | .22 |
| Small for gestational age | $20 341 (0.187) | .03 | $22 262 (0.22) | .01 | −$2295 | .63 | $1041 | .81 | $4922 | .15 | $3532 | .28 |
| Tertiary facility | $55 336 (0.51) | <.001 | $74 057 (0.731) | <.001 | $58 762 | <.001 | $48 759 | <.001 | $0 | $0 | ||
| Diagnosis (ref HLHS) | ||||||||||||
| Other SV | −$17 981 | .45 | −$28 552 | .19 | $7964 | .44 | $6290 | .48 | −$7951 | .45 | −$9319 | .37 |
| TA | −$19 809 | .18 | −$26 006 | .06 | −$11 780 | .10 | −$10 439 | .08 | $2745 | .59 | $4341 | .42 |
| PA/IVS | $4822 | .82 | −$8287 | .66 | −$6372 | .56 | −$13 346 | .18 | −$2181 | .80 | $1995 | .82 |
| Truncus | $19 648 | .29 | −$12 495 | .49 | −$15 823 | .09 | −$15 060 | .07 | $2777 | .68 | $2062 | .76 |
| Ebstein anomaly | −$99 925 | <.001 | −$174 653 | <.001 | −$29 291 | .02 | −$25 653 | .03 | $9445 | .40 | $9844 | .38 |
| PA/VSD | $15 317 | .34 | −$5974 | .70 | $6368 | .451 | $1997 | .79 | −$176 | .98 | $4114 | .56 |
| DORV/TGA | $1544 | .94 | −$9336 | .62 | −$5713 | .56 | −$2965 | .73 | $2520 | .74 | $4807 | .53 |
| DTGA | $23 734 | .07 | −$3450 | .78 | −$36 208 | <.001 | −$31 563 | <.001 | −$7592 | .22 | −$5363 | .38 |
| TOF | −$40 265 | .001 | −$69 896 | <.001 | −$26 791 | <.001 | −$22 443 | <.001 | $1166 | .80 | $2278 | .63 |
| DORV | −$48 680 | .07 | −$73 478 | .002 | $499 | .97 | −$17 362 | .15 | $2300 | .85 | $5376 | .66 |
| IAA | $3205 | .89 | −$28 734 | .16 | −$43 460 | <.001 | −$36 321 | <.001 | $12 704 | .10 | $15 171 | .07 |
| TAPVR | −$15 862 | .39 | −$38 894 | .02 | −$40 522 | .001 | −$34 476 | .001 | −$30 506 | .02 | −$29 797 | .02 |
| Coarctation | −$81 843 | <.001 | −$105 868 | <.001 | −$44 072 | <.001 | −$42 836 | <.001 | −$9548 | .08 | −$9109 | .09 |
| Noncardiac anomaly | $18 826 (0.173) | .09 | $10 551 (0.104) | .29 | $8917 | .12 | $8562 | .08 | $8413 | .03 | $7807 | .05 |
| Gestational age (wk) | −$7904 (−0.073) | <.001 | −$9064 (−0.089) | <.001 | −$833 | .25 | −$345 | .58 | $1195 | .04 | $1293 | .03 |
| Chronic conditions | ||||||||||||
| +1 | $60 075 (0.55) | <.001 | $50 130 (0.513) | <.001 | $12 558 | .003 | $10 699 | .003 | $4561 | .16 | $4242 | .17 |
| >+2 | $118 021 (1.08) | <.001 | $102 724 (1.05) | <.001 | $39 798 | <.001 | $31 495 | <.001 | $12 503 | .002 | $11 536 | .003 |
Bold values indicate significance P <.05 in model.
*
Additional predictors included in the model were sex, maternal race, maternal age, insurance and geographic poverty, and rurality based on census tract of maternal address at birth.
†
Coefficients for multivariable regression only presented for model for first year of life. Because 2-part models were used for older age groups, only the marginal change in cost is presented.