Table VII.
Multivariable regression model of factors associated with inpatient hospital days/LOS in children with CCHD by age*
| Factors | 0-Year 1 (n = 1434) |
Years 2-5 (n = 943) |
Years 6-10 (n = 432) |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total cohort |
Survivors only |
Total cohort |
Survivors only |
Total cohort |
Survivors only |
|||||||
| Marginal Δ† | P value | Marginal Δ† | P value | Marginal Δ† | P value | Marginal Δ† | P value | Marginal Δ† | P value | Marginal Δ† | P value | |
| Prenatal diagnosis | 2.7 | .114 | −0.6 | .71 | 1.0 | .31 | 0.8 | .33 | 1.3 | .15 | 1.7 | .11 |
| Additional major CHD | 5.1 | .061 | 4.7 | .08 | 3.2 | .03 | 3.0 | .02 | 2.7 | .04 | 2.0 | .09 |
| Year of birth | 0.2 | .238 | 0.0 | .80 | −0.3 | .04 | −0.2 | .14 | −0.1 | .56 | −0.1 | .55 |
| Small for gestational age | 6.8 | .001 | 8.3 | <.001 | −0.3 | .78 | 0.6 | .56 | 1.2 | .15 | 0.8 | .32 |
| Tertiary facility | 13.9 | <.001 | 15.3 | <.001 | 8.2 | .01 | 6.9 | .01 | 0 | 0 | ||
| Diagnosis (ref HLHS) | ||||||||||||
| Other SV | 0.6 | .91 | −5.0 | .33 | 1.7 | .50 | 1.3 | .55 | −2.9 | .26 | −3.4 | .22 |
| TA | 1.3 | .70 | −3.4 | .30 | −2.1 | .22 | −2.0 | .15 | 0.2 | .84 | 0.5 | .67 |
| PA/IVS | 2.1 | .66 | −2.1 | .63 | −2.9 | .26 | −4.7 | .05 | −1.1 | .60 | −0.3 | .88 |
| Truncus | 6.3 | .13 | −3.9 | .35 | −4.9 | .04 | −5.1 | .01 | 0.1 | .93 | 0.0 | .99 |
| Ebstein anomaly | −16.0 | <.001 | −31.5 | <.001 | −6.1 | .04 | −4.9 | .08 | 3.1 | .34 | 3.1 | .34 |
| PA/VSD | 6.8 | .07 | −0.9 | .80 | 0.0 | .99 | −1.0 | .54 | −1.1 | .50 | 0.1 | .96 |
| DORV/TGA | 1.9 | .69 | −3.9 | .38 | −2.6 | .27 | −1.9 | .35 | −0.3 | .88 | 0.4 | .83 |
| DTGA | 6.9 | .02 | −2.2 | .45 | −9.1 | <.001 | −8.1 | <.001 | −1.8 | .23 | −1.5 | .33 |
| TOF | −4.3 | .10 | −14.2 | <.001 | −7.2 | <.001 | −6.5 | <.001 | −0.2 | .84 | 0.0 | .97 |
| DORV | −5.3 | .37 | −15.1 | .01 | −0.5 | .87 | −4.1 | .15 | −2.4 | .42 | −1.5 | .62 |
| IAA | 5.7 | .26 | −3.7 | .43 | −10.5 | <.001 | −9.4 | <.001 | 3.0 | .16 | 3.7 | .13 |
| TAPVR | −2.5 | .54 | −10.5 | .01 | −7.6 | .01 | −6.6 | .01 | −5.2 | .09 | −5.6 | .10 |
| Coarctation | −10.5 | <.001 | −19.0 | <.001 | −8.7 | <.001 | −8.8 | <.001 | −1.9 | .15 | −1.9 | .15 |
| Noncardiac anomaly | 1.8 | .47 | 0.5 | .84 | 1.0 | .44 | 0.8 | .49 | 1.2 | .20 | 1.1 | .27 |
| Gestational age (wk) | −2.4 | <.001 | −2.8 | <.001 | −0.2 | .29 | −0.1 | .34 | 0.1 | .49 | 0.1 | .33 |
| Chronic conditions | 1.1 | |||||||||||
| +1 | 14.4 | <.001 | 12.2 | <.001 | 3.6 | .001 | 2.9 | .001 | 1.0 | .21 | 0.9 | .26 |
| >+2 | 31.2 | <.001 | 27.2 | <.001 | 11.0 | <.001 | 8.8 | <.001 | 2.7 | .02 | 2.5 | .03 |
Bold values represent significance of P <.05 in model.
*
Additional predictors included in the model were sex, maternal race, maternal age, insurance and geographic poverty, and rurality based on census tract of maternal address at birth.
†
Marginal change represents change in hospital days.