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. 2020 Jan 9;77(22):4675–4691. doi: 10.1007/s00018-019-03432-7

Fig. 2.

Fig. 2

Selectivity profile of NPY derivatives at human Y receptors. Receptor activation was measured by accumulation of cellular inositol phosphates downstream of a chimeric Gαiq protein (GαqΔ6i4myr) that re-routes the native Gi/o pathway to the phospholipase pathway. Shown is mean ± SEM of n ≥ 3 independent experiments conducted in triplicate. Numerical values can be found in Table 2