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The SNARE/SM Munc18-1 and SNAP-25 in plantaris muscles of trained ALS mice. a Run and swim normalize upregulated pMunc18-1, while Munc18-1 is never modified. The ratio pMunc18-1/Munc18-1 is also normalized after both protocols. b SNAP-25 is decreased by swim and pSNAP-25 (S187) and (T138) are significatively increased despite the trainings. Data are mean value ± SD, *p < 0.05, **p < 0.01, ***p < 0.001. *Versus Untrained WT mice; #versus Untrained ALS; +versus Run ALS mice
