Table 1.

Summary of base-editing rates using BE4-Gam system in porcine embryos by injecting single sgRNA

Target genes	No. of zygotes	No. of 2-cell (%)	No. of blastocysts (%)	No. of mutants (%)	No. of target mutants (%)	No. of bystander editing (%)	No. of indels (%)	No. of C to non-T (%)
GGTA1	60	17 (28.3)	6 (10.0)	4/6 (66.7)	4/6 (66.7)	2/6 (33.3)	0/6 (0)	0/6 (0)
B4GalNT2	60	22 (36.7)	9 (15.0)	6/9 (66.7)	6/9 (66.7)	1/9 (11.1)	0/9 (0)	0/9 (0)
CMAH	60	19 (31.7)	7 (11.7)	5/7 (71.4)	5/7 (71.4)	0/7 (0)	0/7 (0)	0/7 (0)