Table 3.

Summary of base-editing rates using BE4-Gam system in PFFs by transfecting three sgRNAs simultaneously

Target genes	No. of mutants (%)	No. of target mutants (%)	No. of bystander editing (%)	No. of indels (%)	No. of C to non-T (%)	No. of double genes mutants (%)	No. of three genes mutants (%)
GGTA1	10/53 (18.8)	10/53 (18.8)	2/53 (3.77)	0/53 (0)	2/53 (3.77)	7/53 (13.2)	4/53 (7.5)
B4GalNT2	14/53 (26.4)	14/53 (26.4)	0/53 (0)	0/53 (0)	2/53 (3.77)
CMAH	8/53 (15.1)	8/53 (15.1)	0/53 (0)	0/53 (0)	1/53 (1.88)