Fig. 1.

a Polysome profiles of S2 cells expressing HttQ15 and HttQ138. Inset show images of S2 cells expressing RFP tagged HttQ15 and HttQ138. b Quantitation of Polysome/80S ratio. Data is from n = 4 experiments and is represented as a relative fold change for HttQ138 compared to HttQ15. Error bars represent SEM and significance is tested using unpaired one-tailed t test. c Polysome profiles of Yeast expressing HttQ25 and HttQ103. Inset show images of cells expressing GFP tagged HttQ25 and HttQ103. d Quantitation of Polysome/80S ratio from HttQ25 and HttQ103 expressing Yeast. Data from n = 3 experiments represented as a relative fold change of HttQ103 compared to HttQ25. Error bars represent SEM and significance is tested using unpaired one-tailed t-test