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Structural domain overview of LSD1 and LSD2. Both LSD1 and LSD2 contain the catalytic amine oxidase-like domain (AOL), two subdomains of LSD1 AOL domain are shown in green (FAD-binding subdomain) and in reseda (substrate binding subdomain), and a SWIRM domain (shown in red). Tower domain (shown in yellow) and ZFs domain (shown in blue) are unique for LSD1 and LSD2, respectively. The N-terminal flexible region and the C-terminal tail are colored in gray
