Table 1.

Non-histone substrates of LSD1 demethylation

Substrate	Sites	Effects	References
p53	K370Me2	Represses transcription activity	[7]
DNMT1	K142Me12	Stabilization	[72]
E2F1	K185Me1	Stabilization	[45]
MYPT1	K442Me1	Destabilization	[44]
STAT3	K140Me2	Promotes transcription activity	[11]
ERα	K266Me1	Promotes transcription activity	[73]
HIF-1α	K391Me2	Stabilization	[46]
MTA1	K532Me2	Switches to its coactivator function	[74]
AGO2	K726Me1	Stabilization	[47]