Fig. 6.

ODN inhibits reactive oxygen species and lipid oxidation product malondialdehyde accumulation in MPTP-treated mice. Quantification of the levels of reactive oxygen species (ROS) and malondialdehyde (MDA) in the substantia nigra pars compacta (SNpc) (a, c) and striatum (b, d) 7 days after treatment with NaCl (Sham), MPTP (3 × 20 mg/kg), ODN (10 ng/10 µl) and MPTP + ODN. Each value, expressed as a percentage of control, represents the mean (± SEM) obtained from 10 animals and statistical analysis was conducted by ANOVA followed by Bonferroni’s test. *P < 0.05, **P < 0.01 vs saline-treated mice; ^# P < 0.05; ^## P < 0.01 vs MPTP-treated mice