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. 2019 Mar 15;76(12):2299–2328. doi: 10.1007/s00018-019-03062-z

Table 2.

Sequence of selected CDPK autoinhibitory/junction domains

CDPK Species Autoinhibitory/junction domain Identity (%)
UniProt ID
SK5 Soybean (Glycine max) 298APDKPLDSAVLSRLKQFSAMNKLKKMALRVI328

P28583

OsCPK11 Rice (Oryza sativa)_ 377APDKPLDSAVLSRLKQFSAMNKLKKMALRVI407

100

Q852N6

NtCDPK3 Tobacco (Nicotiana tabacum) 378APDKPLDSAVLSRMKQFSAMNKLKKMALRVI408

96.8

Q93YF3

AtCPK11 Mouse-ear cress (Arabidopsis thaliana) 290APDKPLDPAVLSRLKQFSQMNKIKKMALRVI320

90.3

Q39016

PfCPK1a Protozoan (Plasmodium falciparum) 344LSNMRKFEGSQKLAQAAILFI364

P62343

TgCDPK1b Protozoan (Toxoplasma gondii)

320VPSLDNAILNIRQFQGTQKLAQAALLYMGSKLTSQDETKELTAIFHKMDK369

420GYIEYSEFVTVAMDRKTLLSRERLERAFRMFD451

81.8

Q9BJF5

In higher plant CDPKs the residues in bold indicate changes with respect to soybean CDPK, and a conserved functionally important phenylalanine residue is underlined in bold [32]. In P. falciparum and T. gondii the underlined segment is highly conserved and may represent a functionally important segment

aSmall segment of the autoinhibitory/junction domain [32]

bTwo helical segments of the autoinhibitory/junction domain [232]