Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Mutually exclusive ‘sibling’ subunits; for example, within SWI/SNF chromatin remodeling and polycomb repressive complex, PRC2. a SWI/SNF complex contains either one of the ATPase counterparts BRG1 or BRM; or b ARID1A or ARID1B. c PRC2 complex contains either one of the two enhancer of zeste homologues EZH1 or EZH2 catalytic subunits. Concurrent downregulation of both ‘sibling’ factors renders the complex inactive and results in synthetic lethality (SL)
