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Potential arrangement of proteins within the vertebrate auditory transduction complex. By interacting with multiple auxiliary proteins (TMIE, LHFPL5, PCDH15, and CIB2), TMC1 channel may form the pore of auditory transduction complex (modified from Corey et al. [67]). For simplicity, a TMC monomer is depicted in the model figure (according to recent structural studies, TMC channels form dimers)
