Fig. 2.

Inhibitors of Protein Methyltransferase Families. a, b Phylogeny of protein methyltransferase domains from SET-domain and seven-β-strand PMT families. Indicated with a blue circle, are proteins with inhibitors of at least 5 µM potency (IC₅₀ or Ki) described in the BindingDB database [157] Those with a chemical probe available are indicated with a red circle (https://www.thesgc.org/chemical-probes)