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. 2018 Mar 28;75(18):3441–3456. doi: 10.1007/s00018-018-2807-y

Fig. 3.

Fig. 3

Relative velocity in the presence of 50 μM substrate as a function of IDE concentration for the chymotrypsin-like (circle), trypsin-like (cross) and caspase-like (asterisk) activity of h20S. Continuous lines are the non-linear least-squares global fitting of all three enzymatic activities according to Eq. (2e), employing parameters reported in Tables 1 and 2