The long non-coding RNA H19 promotes cancer cell proliferation. aH19 promotes the G1/S transition in breast and colorectal cancer cells, in esophageal squamous cell carcinoma and in pancreatic ductal adenocarcinoma [32, 40, 62, 67]. bH19 sponges several miRNAs to allow β-catenin and DNMTs expression in colorectal, breast, and bladder cancer, respectively [29, 64, 68]