Table 1.
ncRNAs | Targets/CVDs | Pro- or anti-apoptosis | References |
---|---|---|---|
miR-1 | Bcl-2/MI | Promotes apoptosis | [22] |
miR-133a | Caspase-9/MI | Inhibits apoptosis | [24] |
miR-17-92 cluster | STAT3/MI, HF | Induces apoptosis | [63, 64] |
miR-21 | Bcl-2/MI | Anti-apoptotic | [65] |
miR-30 | P53/MI | Anti-apoptotic | [35] |
miR-199a | Hif1α, Sirt1/MI | Anti-apoptotic | [29] |
miR-320 | Hsp20/MI | Pro-apoptotic | [30] |
miR-149 | Puma/MI | Decreases apoptosis | [66] |
miR-761 | Mff/MI | Promotes apoptosis | [67] |
miR-499 | Calcineurin/MI | Inhibits apoptosis | [68] |
miR-214 | Pten/MI | Anti-apoptotic | [69] |
miR-145 | Bnip3/MI | Decreases apoptosis | [70] |
miR-378 | Caspase-3/MI | Anti-apoptotic | [71] |
miR-195 | Sirt1/lipotoxic cardiomyopathy | Pro-apoptotic | [72] |
miR-34a | Sirt1/coronary artery disease | Promotes apoptosis | [73] |
miR-184 | Bcl-xL, Bcl-w/MI | Pro-apoptotic | [31] |
miR-140 | Mfn1/MI | Induces apoptosis | [38] |
miR-421 | Pink1/MI | Promotes apoptosis | [4] |
miR-324-5p | Mtfr 1/MI | Anti-apoptotic | [42] |
miR-361 | Phb1/MI | Pro-apoptotic | [41] |
miR-208a | GATA4/DOX cardiotoxicity | Promotes apoptosis | [45] |
miR-532-3p | ARC/DOX cardiotoxicity | Pro-apoptosis | [46] |
LncRNA-CARL | miR-539, Phb2/MI | Inhibits apoptosis | [56] |
CircRNA-HRCR | miR-223, arc/cardiac hypertrophy | Anti-apoptotic | [60] |