Table 1.
Items of quality management for clinical grade iPSC-derived NPCs
| General characterization | Cell morphology |
| Cell number | |
| Survival rate | |
| Cell proliferation | |
| Cell cycle | |
| Marker expression analysis | Genomic marker |
| Protein marker | |
| Cell surface marker | |
| Genomic analysis | Chromosome/Karyotypte |
| Human Leucocyte Antigen | |
| Copy number variant | |
| Methylation | |
| Functional analysis | Differentiation |
| Neuronal conduction | |
| Secretion of trophic factors | |
| Safety analysis | Sterility |
| Virus test | |
| Tumorigenicity after graft |