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. 2017 Oct 9;75(6):989–1000. doi: 10.1007/s00018-017-2676-9

Table 1.

Items of quality management for clinical grade iPSC-derived NPCs

General characterization Cell morphology
Cell number
Survival rate
Cell proliferation
Cell cycle
Marker expression analysis Genomic marker
Protein marker
Cell surface marker
Genomic analysis Chromosome/Karyotypte
Human Leucocyte Antigen
Copy number variant
Methylation
Functional analysis Differentiation
Neuronal conduction
Secretion of trophic factors
Safety analysis Sterility
Virus test
Tumorigenicity after graft