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Scaffold hopping of benzimidazoline imine
| ||
|---|---|---|
| No. | X | IC50 (nM)a |
|
| ||
| 6v | NCH3 | >1000 |
| 8a | O | >1000 |
| 8b | S | >1000 |
| 10 |
|
>1000 |
| 11 |
|
494 |
| 12 |
|
>1000 |
The cytotoxicity activities of individual compound to MCF7 cells were determined by the MTT assay. Data are the mean of triplicate determinations.
