Table 1.
Identification of differentially abundant proteins from nano-enriched proteomic analysis of plasma samples
| Description | Gene name | P value | Maximum fold change |
|---|---|---|---|
| s-GO: 0 h versus 6 h (n = 3) | |||
| Downregulated | |||
| cDNA FLJ26936 fis, clone RCT06808 | 0.019 | 5.52 | |
| Upregulated | |||
| Platelet endothelial cell adhesion molecule | PECAM1 | 0.016 | 2.05 |
| Sorcin | SRI | 0.043 | 15.07 |
| us-GO: 0 h versus 6 h (n = 3) | |||
| Upregulated | |||
| Fibroblast growth factor-binding protein 2 | FGFBP2 | 0.024 | 1.91 |
| Annexin | 0.027 | 2.55 | |
| Proteoglycan 1, secretory granule, isoform CRA_a | PRG1 | 0.041 | 4.14 |
| Sorcin | SRI | 0.046 | 21.16 |
| Air versus s-GO (6 h) (n = 10) | |||
| Downregulated | |||
| Tubulin alpha-4A chain | TUBA4A | 0.007 | 3.99 |
| Immunoglobulin G heavy chain | 0.015 | 20.71 | |
| Prolactin-inducible protein | PIP | 0.017 | 2.22 |
| Alpha-1-antichymotrypsin (fragment) | SERPINA3 | 0.036 | 2.76 |
| HRV Fab 026-VL (fragment) | 0.042 | 1.53 | |
| 60S ribosomal protein L18 (fragment) | RPL18 | 0.045 | 515.74 |
| Upregulated | |||
| Uncharacterized protein DKFZp686N02209 | DKFZp686N02209 | 0.031 | 1.36 |
| Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 | INPP5D | 0.031 | 1.83 |
| Collagen alpha-1(IV) chain | COL4A1 | 0.036 | 1.74 |
| Putative ciliary rootlet coiled-coil protein 2 | CROCC2 | 0.040 | 1.48 |
| Air versus us-GO (6 h) (n = 7) | |||
| Downregulated | |||
| Coagulation factor XII | F12 | 0.006 | 5.27 |
| Apolipoprotein B protein (fragment) | APOB | 0.006 | 3.87 |
| Plasma protease C1 inhibitor | SERPING1 | 0.02 | 1.46 |
| Alpha-2-HS-glycoprotein | AHSG | 0.02 | 1.66 |
| cDNA FLJ41054 fis, clone STOMA1000189 | 0.03 | 9.00 | |
| cDNA FLJ90052 fis, clone HEMBA1002767, highly similar to Beta-1,4-galactosyltransferase 2 (EC 2.4.1.-) | 0.049 | 1.70 | |
| Immunoglobulin heavy chain variable region (fragment) | 0.049 | 18.05 | |
The listed values are from independent biological samples for each group (from top to bottom table: n = 3, n = 4, n = 10, n = 7). Data were filtered in Pyrogenesis LC-MC to present a 1% false discovery rate. Comparisons between groups conducted using one-way analysis of variance, with only proteins demonstrating P < 0.05 shown. cDNA, copyDNA.