Table 4.

Linear regression model results for the log2 fold change of B28/P28 Spike-specific T cell response.

	Estimate	Standard Error	p-value
Intercept
	-0,155	0,359	0,667
Age (centralized)
	0,000	0,018	0,996
Sex
Male	Ref.
Female	0,546	0,190	0,004
Months between primary-booster (centralized)
	-0,255	0,299	0,394
Vaccine combination
BNT162b2/BNT162b2	Ref.
BNT162b2/mRNA-1273	0,711	0,279	0,011
mRNA-1273/BNT162b2	-0,726	0,367	0,049
CMV status
Negative	Ref.
Positive	0,910	0,252	0,000
Log fold change (B0/P28)
	0,552	0,051	0,000
Months between primary-booster (centralized) * Age (centralized)
	0,018	0,008	0,027
Months between primary-booster (centralized) * CMV status
	0,296	0,299	0,324
Age (centralized) * CMV status
	-0,020	0,018	0,258
Months between primary-booster (centralized) * Age (centralized) * CMV status
	-0,038	0,010	0,000

R² = 0.517.

*indicates an interaction term; Ref. is reference.