Table 1.

Comparison of CPADS with other tumour drug sensitivity analysis web pages

	CPADS	canSAR [18]	CellMiner [19]	GSCALite [21]	PharmacoDB [22]	DRESIS [23]
Dataset	TCGA, GDSC, GEO(including NCI-60)	TCGA, ICGC	GDSC, CCLE, CTRP, NCI-60	GDSC, TCGA, GTEx	NCI-60, GDSC, PRISM, CCLE, gCSI	DrugBank, CCNSC, TTD
Sample	~29 000	~25 000	1400	23 594	1757	–
Cancer Type	44	26	60	33	30	125
Cancer Analysis Module	①Differential expression gene analysis	Genomic data analysis	Correlation analysis	①Genomic data analysis	①Genomic data analysis	Resistance mechanisms analysis
	②Correlation analysis			②Pathway activity	②Correlation analysis
	③Pathway analysis(GSEA, ssGSEA, Pathview)			③miRNA network	③Drug sensitivity
	④Drug analysis			④Drug sensitivity
	⑤Gene perturbations
Parameters Customization	YES	NO	NO	NO	NO	NO
Colour Customization	YES	NO	NO	NO	NO	NO

TCGA, The Cancer Genome Atlas; GDSC, The Cancer Genome Atlas; GEO, Gene Expression Omnibus; GSEA, Gene Set Enrichment Analysis; ssGSEA, Single sample gene set enrichment analysis; ICGC, International Cancer Genome Consortium; CCLE, Cancer Cell Line Encyclopedia; CTRP, Cancer Therapeutics Response Portal; NCI, National Cancer Institute; GTEx, Genotype-Tissue Expression; PRISM, Profiling Relative Inhibition Simultaneously in Mixtures; gCSI, Genentech Cell Line Screening Initiative; CCNSC, Cancer Chemotherapy National Service Center; TTD, Therapeutic Target Database.